Based on the game by M no Violet. Sequel to Night Shift Nurses.
The elite doctor Kuwabara Souichirou couldn't forget his feelings towards Nanase Ren, whom he had loved in his youth. He changed the hospitals he worked at, one after another, to look for her, and finally he met her again at the St. Cattleya Hospital. However, her attitude was remote and his love couldn't be fulfilled. To make matters worse, he received photographs depicting Ren being molested. Ren had been turned into a lewd woman by Hirasaka through the woman body experiment when she was at the St. Julianna Hospital. He was disappointed and he lost his mind. Kazama Mana, who was a nurse of the gynecology and obstetrics section, loved Kuwabara, and she resembled Ren. Taking advantage of her feelings, Kuwabara raped her and took her virginity while shouting the name of Ren.
